SODIUM THIOSULPHATE DECREASES BLOOD CYANIDE CONCENTRATION FOLLOWING SODIUM NITROPRUSSIDE
نویسندگان
چکیده
منابع مشابه
Cyanide and thiocyanate concentrations following sodium nitroprusside infusion in man.
Twenty-six patients, receiving an infusion of sodium nitroprusside (SNP) during surgery, had considerable increases in both red cell and plasma cyanide concentration, but only small changes in plasma thiocyanate concentration. There was a linear relationship between both plasma and RBC cyanide concentrations and the total dose of SNP. The expired cyanide concentration followed the changes in th...
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The goal of hyptensive anesthesia is the safe reduction of intraoperative blood loss, thus reducing transfusion risks. Previous hypotensive technics had a narrow margin of safety in that cardiac output was usually reduced in proportion to the degree of induced hypotension. This is in contrast to the results of our study, in which Sodium Nitroprusside was used as the sole hypotensive agent. Ni...
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Brain cytochrome oxidase activity was measured after the in vitro addition of potassium cyanide (KCN) or sodium nitroprusside (SNP). Activity of cytochrome oxidase was sensitive to KCN; however, this activity was unaffected by SNP. In SNP- and KCN-treated animals brain cytochrome oxidase activities were measured. At 3 min after SNP injection, inhibition of the enzymatic activity was the same as...
متن کاملBlood cyanide and thiocyanate concentrations produced by long-term therapy with sodium nitroprusside.
Blood cyanide (HCN) or plasma thiocyanate (SCN) concentrations, or both, were measured in 30 patients (ages 11 months-72 yr) receiving sodium nitroprusside (SNP) for 12-314 h. Sequential measurements in three of these patients (infused 5, 12 and 13 days) showed that HCN concentrations varied with dose rate, while SCN concentrations increased linearly with increasing SNP dose. The accumulated da...
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To the Editor, The Indian Medical Gazette. Sir,?In your issue for last November, p. 641, in the abstract from Dr. Johnstone's article on acute mercurial poisoning, it is stated that ' we use sodium thiosulphate both by mouth and intravenously. Its intravenous use has not proved valuable in experimental animals, although it has been shown to be harmless Certain writers consider it of value in po...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1988
ISSN: 0007-0912
DOI: 10.1093/bja/60.6.744